Investigator Sponsored Studies

The mission of the United Therapeutics Corporation Investigator Sponsored Study (ISS) program is to support independent basic science, pre-clinical, and clinical research that will expand the scientific knowledge base and ultimately improve healthcare delivery in disciplines aligned with United Therapeutics Corporation product portfolio. We provide support across all phases of development, spanning both interventional and non-interventional research.

The program has supported studies evaluating novel use of approved UT therapies, observational studies, such as epidemiological or outcomes based research, prostacyclin receptor pharmacology research, and research evaluating novel endpoints or diagnostic tools for use in pulmonary hypertension.

Data Query Program
The purpose of the Data Query program is to allow investigators to propose independent post-hoc analyses of UT clinical data sets.


To submit a study concept or data query concept, please visit and create an account. Once signed in, select “Investigator Sponsored Study” from the request menu to submit your concept.

For questions, please email